{"id":5215,"date":"2022-10-24T23:26:10","date_gmt":"2022-10-24T23:26:10","guid":{"rendered":"https:\/\/respiratoryresearch.org\/staging\/3073\/?page_id=5215"},"modified":"2026-08-14T00:26:32","modified_gmt":"2026-08-14T00:26:32","slug":"allopentrials","status":"publish","type":"page","link":"https:\/\/respiratoryresearch.org\/staging\/3073\/allopentrials\/","title":{"rendered":"All Open Trials"},"content":{"rendered":"

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COPD<\/strong><\/em><\/h1>\n

COPDGene Study<\/h2>\n
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ClinicalTrials.gov Identifier\u00a0NCT00608764<\/a><\/p>\n

This nationwide multicenter study aims to identify the genetics behind why some smokers get COPD and others do no not. The study is still open to enrollment but only participants who have never smoked.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Embark<\/h2>\n

ClinicalTrials.gov Identifier\u00a0NCT06883305<\/a><\/p>\n

This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety and efficacy of tezepelumab in adults with moderate to very severe chronic obstructive pulmonary disease (COPD) receiving inhaled maintenance therapy and having had at least 2 moderate, or 1 severe, COPD exacerbations in the 12 months prior to Visit 1. Subjects will receive monthly subcutaneous injection of one of two different doses of tezepelumab, or placebo, with a maximum treatment duration of 76 weeks and a minimum of 52 weeks. The study also includes a off-treatment safety follow-up period of 12 weeks.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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NMF Study<\/h2>\n

We are currently looking for volunteers for a research study to better understand how fatigue of the breathing muscles alters leg muscle performance and how this affects people with or without chronic obstructive pulmonary disease (COPD) and their ability to exercise.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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PRISm<\/h2>\n

We are currently looking for volunteers for a research study that we are conducting to better understand a pulmonary condition termed Preserved Ratio Impaired Spirometry (PRISm) and how this affects people\u2019s everyday life and their ability to exercise. People with PRISm have abnormal lung function tests, do not have Chronic Obstructive Pulmonary Disease but do have shortness of breath during physical activity.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Wearables 2<\/h2>\n

Our research teams at the Lundquist Institute at Harbor-UCLA Medical Center and Caltech, are testing an experimental skin sensor to see if it can measure markers of lung infection without taking a blood sample. We are seeking your participation in our research to help develop this COPD flare-up early warning system.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Healthy<\/strong><\/em><\/h1>\n

mCPET Healthy Adults Study<\/h2>\n

Sign Up Here<\/a><\/p>\n

This study will develop a reference values in healthy participants for a new diagnostic test of exercise capacity (called mCPET).<\/p>\n

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Pulmonary Hypertension<\/strong><\/em><\/h1>\n

UCAPE\/SEARCH Study<\/h2>\n

ClinicalTrials.gov Identifier\u00a0NCT05568927<\/a><\/p>\n

The project will validate a clinical decision tree designed to improve timely diagnosis and treatment of patients with pulmonary embolism.<\/p>\n

The proposed project will validate a clinical decision tree to distinguish among the various discrete outcomes cost-effectively through a hierarchical series of tests with the acronym SEARCH (for symptom screen, exercise function, arterial perfusion, resting heart function, confirmatory imaging and hemodynamics). Each step of the algorithm sorts a subset of patients into a diagnostic category unequivocally in a cost-effective manner. The categories are mutually exclusive and collectively exhaustive, so that each case falls into one, and only one, category.[\/vc_column_text][\/vc_column][vc_column width=”1\/3″][vc_gallery interval=”5″ images=”5729,5731,5732,5733,5734″ img_size=”large” onclick=”” css=””][vc_widget_sidebar top_margin=”page-margin-top” sidebar_id=”sidebar-home-right-style-2″]

Want to Learn More? Send Us a Message!<\/h3>